Haloperidol Intravenous Injection for Adults

Who can administer

Administration RESTRICTED - see Appendix 1 

Important information

• There are numerous important interactions (eg QTc, Parkinson's) - check BNF

Available preparations

Serenace 5mg per 1ml ampoule 

Reconstitution

Already in solution
Draw up using a 5 micron filter needle

Infusion fluids

Not required - product ready for use

Methods of intravenous administration

Slow intravenous injection ^{(ref 1)}

• Administer over 3 to 5 minutes
• Maximum rate of 5mg/min in an emergency
• Can dilute with sodium chloride 0.9% or glucose 5% to produce a suitable volume to aid slow administration

Dose in adults

Delirium Management in Critical Care ^{(ref 2)}

• Usual dose: 2.5mg every 6 hours, adjusted according to response 
• Maximum dose: 20mg in 24 hours
• Older patients: maximum of 5mg in 24 hours

Monitoring

• Monitor blood pressure, heart rate, ECG ^{(ref 1)}
• Monitor infusion site frequently - extravasation may cause local tissue damage ^{(ref 1)}

Storage

Store below 25⁰C

References

SPC March 2011

1. Injectable Medicines administration guide, downloaded from Medusa 10/02/2025

2. UHG Critical Care Department Delirium Management algorithm V2.0 2024 

Therapeutic classification

Antipsychotic